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tert-Butylchlorodiphenylsilane 叔丁基二苯基氯硅烷

规格: 98%, SpcSeal

CAS: 58479-61-1

产品编号: H50943

MDL: MFCD00000497

品牌: INFI

Chemical Name	tert-Butylchlorodiphenylsilane
MDL Number	MFCD00000497
Synonym	tert-Butyldiphenylsilyl chloride
EC Number	261-282-0
CAS Number	58479-61-1
Beilstein Registry Number	644023
PubChem Substance ID	87564159
Chemical Name Translation	叔丁基二苯基氯硅烷
Reaxys-RN	644023
LabNetwork Molecule ID	LN00190961
Canonical SMILES	CC([Si](C1=CC=CC=C1)(C2=CC=CC=C2)Cl)(C)C

硅化剂，用于保护醇和制备硅醚

{ALF} Cleavage occurs readily with TBAF in THF: Org. Synth. Coll., 9, 4 (1998). For use of K10 clay in aqueous MeOH, see: J. Org. Chem., 61, 9026 (1996). Cleavage with BBr3 leads directly to the corresponding alkyl bromides: J. Org. Chem., 53, 3111 (1988).

{ALD} Merck: 14,10402

{ALF} Silylating agent (see Appendix 4) for the formation, with e.g. imidazole, of t-butyldiphenylsilyl (TBDPS) ethers of alcohols: Can. J. Chem., 53, 2975 (1975); Org. Synth. Coll., 9, 139 (1998). Alternative to tert-Butyldimethylchlorosilane, A13064, allowing selective protection of primary alcohols in the presence of secondary, using DMAP/ pyridine: Helv. Chim. Acta, 69, 1273 (1986), or DMAP/ triethylamine: Tetrahedron Lett., 99 (1979); 26, 1185 (1985). TBDPS ethers tend to be more crystalline and are much more stable to acidic conditions than TBDMS. They can also survive acetal formation and cleavage, as well as the acidic conditions required for cleavage of trityl and THP ethers. Silylation rates of hindered alcohols have been increased in the presence of silver nitrate: J. Am. Chem. Soc., 116, 5050 (1994).

{ALF} The silyl copper species derived from the lithio-derivative and CuCN adds to terminal alkynes, giving vinyl copper intermediates which react with electrophiles to give vinyl silanes. The presence of the hindered TBDPS group confers some useful differences in comparison with less hindered silyl groups: J .Chem. Soc., Perkin 1., 1525 (1995); compare Chlorodimethylphenylsilane, A15638. The hindered TBDPS group has also been utilized in the Peterson olefination reaction to promote high (Z)-selectivity: Synthesis, 1223 (2000).

58479-61-1 H50943 tert-Butylchlorodiphenylsilane
叔丁基二苯基氯硅烷

化学属性

Mol. Formula	C16H19ClSi
Mol. Weight	274.86
Density	1.057
Refractive index	1.5650 to 1.5690
Flash Point	110°C
TSCA	Yes
Boiling Point	334.4°C at 760 mmHg
Stability	对湿度敏感
pH	:A

*以上化合物性质及应用等信息仅供参考

电子化学品

催化剂

配体

有机硅

元素分类

其他精细新材料

tert-Butylchlorodiphenylsilane 叔丁基二苯基氯硅烷

规格: 98%, SpcSeal

化学属性

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