{ALD} Beilstein:6,346

{PUB} Comparative Toxicogenomics Database (CTD)|PubChem --- Diphenyl diselenide protects against metabolic disorders induced by acephate acute exposure in rats --- https://pubmed.ncbi.nlm.nih.gov/22778074

{ALF} For a comprehensive review of the preparation of ɑß-unsaturated carbonyl compounds and nitriles by selenoxide elimination, see: Org. React., 44, 1 (1993). Compare also Phenyl­selenenyl­ bromide, A11906 and Phenyl­selenenyl­ chloride, A12751.

{ALF} For introduction of the phenylseleno group by Michael addition, phenylselenol can be generated in situ by borohydride cleavage: Synthesis, 664 (1980).

{ALF} For reviews of the application of organoselenium reagents in organic synthesis, see: Tetrahedron, 34, 1049 (1978); Acc. Chem. Res., 12, 22 (1979); 17, 28 (1984). Monograph: Organoselenium Chemistry, D. Liotta, ed., Wiley, N.Y. (1987).

{ALF} Oxidation of diphenyl diselenide by persulfate in the absence of a nucleophilic counter-ion generates the phenylselenium cation, which adds to alkenes. Molecules with a suitably placed nucleophilic site (alkene, hydroxyl, carbonyl, carboxyl, etc.) can then undergo intramolecular cyclization: J. Org. Chem., 55, 429 (1990); J. Chem. Soc. Perkin 1, 1989 (1993); Synlett, 373 (1994):

{PUB} PubC

{PUB} PubChem --- A Simple Zinc-Mediated Method for Selenium Addition to Michael Acceptors --- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249194

{PUB} PubChem --- Acute Diphenyl Diselenide Treatment Reduces Hyperglycemia But Does Not Change Delta-Aminolevulinate Dehydratase Activity in Alloxan-Induced Diabetes in Rats --- https://pubmed.ncbi.nlm.nih.gov/19043199

{PUB} PubChem --- Diphenyl diselenide [(PhSe)2] inhibits Drosophila melanogaster delta-aminolevulinate dehydratase (delta-ALA-D) gene transcription and enzyme activity --- https://pubmed.ncbi.nlm.nih.gov/17936691

{PUB} PubChem --- Diphenyl diselenide exerts antidepressant-like and anxiolytic-like effects in mice: In